... Starting with 4.5 dev 5, you can expect your Web games to run a little bit more smoothly, without having to do anything. Especially when things get chaotic (for your CPU). It isn’t a silver bullet for poorly optimized games, but it will help nonetheless. Also, note that it cannot do anything for GPU rendering bottlenecks.
... From here on out, the 4.5 release official templates will only support WebAssembly SIMD-compatible browsers in order to keep the template sizes small. We generally aim to maintain compatibility with the oldest devices we can. But in this case, the performance gains are too large to ignore and the chances of users having browsers that are that far out of date is too small relative to the potential benefits.